cataliesw
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The prognosis of cancers is closely related to the number of tumor-associated macrophages (TAMs) with an inverse correlation. An increased number of TAMs is associated with reduced survival. TAMs are generally polarized into either of two extremes, classical activated M1 subtype and alternatively activated M2 subtype. TAMs usually express an M2-like phenotype and participate in tumor angiogenesis, tumor invasion, tumor metastasis, and immunosuppression. Learn more: Tumor-associated Macrophage (TAM) Reprogramming
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